Intrathoracic malignant peripheral nerve sheath tumors: imaging features and implications for management

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Intrathoracic Malignant Peripheral Nerve Sheath Tumor: Histopathological and Immunohistochemical Features

Malignant peripheral nerve sheath tumor (MPNST) is a rare nerve sheath tumor derived from Schwann cells or pleuripotent cells of neural crest. Neurogenic tumors make about 10-20% of all mediastinal tumors. Incidence of MPNST is 0.001% in general population and 0.16% in patients with neurofibromatosis I (NF I). We report a case of 60 year female presenting with progressive cough and breathlessne...

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Intrathoracic malignant peripheral nerve sheath tumors: imaging features and implications for management

BACKGROUND The aim of the study was to analyze the clinical and imaging characteristics of primary intrathoracic malignant peripheral nerve sheath tumors (MPNSTs). PATIENTS AND METHODS In this institutional review board (IRB)-approved retrospective study, clinical and imaging features of 15 patients (eight men; mean age 50 years [range 18-83)] with pathologically proven malignant peripheral n...

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intrathoracic malignant peripheral nerve sheath tumor: histopathological and immunohistochemical features

malignant peripheral nerve sheath tumor (mpnst) is a rare nerve sheath tumor derived from schwann cells or pleuripotent cells of neural crest. neurogenic tumors make about 10-20% of all mediastinal tumors. incidence of mpnst is 0.001% in general population and 0.16% in patients with neurofibromatosis i (nf i). we report a case of 60 year female presenting with progressive cough and breathlessne...

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Intrathoracic Malignant Peripheral Nerve Sheath Tumor: Histopathological and Immunohistochemical Features.

Malignant peripheral nerve sheath tumor (MPNST) is a rare nerve sheath tumor derived from Schwann cells or pleuripotent cells of neural crest. Neurogenic tumors make about 10-20% of all mediastinal tumors. Incidence of MPNST is 0.001% in general population and 0.16% in patients with neurofibromatosis I (NF I). We report a case of 60 year female presenting with progressive cough and breathlessne...

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Intrathoracic paraspinal malignant peripheral nerve sheath tumor.

Schwannoma is the most common nerve sheath tumor in the posterior mediastinum, whereas intrathoracic paraspinal malignant peripheral nerve sheath tumor (MPNST) is quite rare. Both benign and malignant nerve sheath tumors may be symptomatic, rendering clinical differentiation of limited utility. On radiographic imaging, erosion of the ribs and vertebral bodies, irregularity in contour, and inhom...

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ژورنال

عنوان ژورنال: Radiology and Oncology

سال: 2013

ISSN: 1581-3207,1318-2099

DOI: 10.2478/raon-2013-0047